Greg A. Lazar: search on Z-Library

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1

Next generation antibody drugs: pursuit of the 'high-hanging fruit'

Carter, Paul J., Lazar, Greg A.

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 710 KB

english, 2017

2

Automated high throughput microscale antibody purification workflows for accelerating antibody discovery

Luan, Peng, Lee, Sophia, Arena, Tia A., Paluch, Maciej, Kansopon, Joe, Viajar, Sharon, Begum, Zahira, Chiang, Nancy, Nakamura, Gerald, Hass, Philip E., Wong, Athena W., Lazar, Greg A., Gill, Avinash

Journal:

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

3

Enhanced antibody half-life improves in vivo activity

Zalevsky, Jonathan, Chamberlain, Aaron K, Horton, Holly M, Karki, Sher, Leung, Irene W L, Sproule, Thomas J, Lazar, Greg A, Roopenian, Derry C, Desjarlais, John R

Journal:

Nature Biotechnology

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

4

Rational design and engineering of therapeutic proteins

Shannon A. Marshall, Greg A. Lazar, Arthur J. Chirino, John R. Desjarlais

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

5

Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions

Moore, Gregory L., Chen, Hsing, Karki, Sher, Lazar, Greg A.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.95 MB

english, 2010

6

A molecular immunology approach to antibody humanization and functional optimization

Greg A. Lazar, John R. Desjarlais, Jonathan Jacinto, Sher Karki, Philip W. Hammond

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

7

Proteomic comparison of two fractions derived from the transsynaptic scaffold

Greg R. Phillips, Laurence Florens, Hidekazu Tanaka, Zin Z. Khaing, Lazar Fidler, John R. Yates III, David R. Colman

Journal:

Journal of Neuroscience Research

Year:

2005

Language:

english

File:

PDF, 392 KB

english, 2005

8

Hydrophobic core packing and protein design

Greg A Lazar, Tracy M Handel

Journal:

Current Opinion in Chemical Biology

Year:

1998

Language:

english

File:

PDF, 669 KB

english, 1998

9

Modulation of antibody effector function

John R. Desjarlais, Greg A. Lazar

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

10

Biochemical and Structural Studies of the Interaction of Cdc37 with Hsp90

Wei Zhang, Miriam Hirshberg, Stephen H McLaughlin, Greg A Lazar, J.Günter Grossmann, Peter R Nielsen, Frank Sobott, Carol V Robinson, Sophie E Jackson, Ernest D Laue

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 734 KB

english, 2004

11

[American Institute of Aeronautics and Astronautics 47th AIAA Aerospace Sciences Meeting including The New Horizons Forum and Aerospace Exposition - Orlando, Florida ()] 47th AIAA Aerospace Sciences Meeting including The New Horizons Forum and Aerospace Exposition - Energy Deposition applied to a Transverse Jet in a Supersonic Flow

Lazar, Eli, Elliott, Greg, Glumac, Nick

Year:

2009

Language:

english

File:

PDF, 7.44 MB

english, 2009

12

High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants

DiCara, Danielle M., Andersen, Nisana, Chan, Ruby, Ernst, James A., Ayalon, Gai, Lazar, Greg A., Agard, Nicholas J., Hilderbrand, Amy, Hötzel, Isidro

Journal:

Year:

2018

Language:

english

File:

PDF, 2.59 MB

english, 2018

13

Fc-engineered EGF-R antibodies mediate improved antibody-dependent cellular cytotoxicity (ADCC) against KRAS-mutated tumor cells

Martin Schlaeth, Sven Berger, Stefanie Derer, Katja Klausz, Stefan Lohse, Michael Dechant, Greg A. Lazar, Tanja Schneider-Merck, Matthias Peipp, Thomas Valerius

Journal:

Year:

2010

Language:

english

File:

PDF, 619 KB

english, 2010

14

A Novel Interface for High-Throughput Analysis of Biotherapeutics by Electrospray Mass Spectrometry

Park, Hae-Min, Winton, Valerie J., Drader, Jared J., Manalili Wheeler, Sheri, Lazar, Greg A., Kelleher, Neil L, Liu, Yichin, Tran, John C., Compton, Philip D.

Journal:

Analytical Chemistry

Year:

2019

Language:

english

File:

PDF, 769 KB

english, 2019

15

γ-Protocadherins Are Targeted to Subsets of Synapses and Intracellular Organelles in Neurons

Phillips, Greg R., Tanaka, Hidekazu, Frank, Marcus, Elste, Alice, Fidler, Lazar, Benson, Deanna L., Colman, David R.

Journal:

Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 1.06 MB

english, 2003

16

De novo design of the hydrophobic core of ubiquitin

Greg A. Lazar, John R. Desjarlais, Tracy M. Handel

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 4.74 MB

english, 1997

17

Characterizing and Quantitating Therapeutic Tethered Multimeric Antibody Degradation Using Affinity Capture Mass Spectrometry

Li, Wenjing, Srikumar, Neha, Forrest, William F., Ellerman, Diego, Gu, Chen, Tchelepi, Robert, Lazar, Greg A., Liu, Yichin, Tran, John C.

Journal:

Analytical Chemistry

Year:

2020

File:

PDF, 1.08 MB

2020

18

Engineering Fully Human Monoclonal Antibodies from Murine Variable Regions

Matthew J. Bernett, Sher Karki, Gregory L. Moore, Irene W.L. Leung, Hsing Chen, Erik Pong, Duc-Hanh T. Nguyen, Jonathan Jacinto, Jonathan Zalevsky, Umesh S. Muchhal, John R. Desjarlais, Greg A. Lazar

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

19

High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants

DiCara, Danielle M., Andersen, Nisana, Chan, Ruby, Ernst, James A., Ayalon, Gai, Lazar, Greg A., Agard, Nicholas J., Hilderbrand, Amy, Hötzel, Isidro

Journal:

Year:

2018

File:

PDF, 2.59 MB

2018

20

Susceptibility of antibody CDR residues to chemical modifications can be revealed prior to antibody humanization and aid in the lead selection process

Xu, Ankai, Kim, Hok Seon, Estee, Samarkand, ViaJar, Sharon, Galush, William J, Gill, Avinash, Hotzel, Isidro, Lazar, Greg A., McDonald, Paul, Andersen, Nisana, Spiess, Christoph

Journal:

Molecular Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

21

A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens

Moore, Gregory L., Bautista, Cristina, Pong, Erik, Nguyen, Duc-Hanh T., Jacinto, Jonathan, Eivazi, Araz, Muchhal, Umesh S., Karki, Sher, Chu, Seung Y., Lazar, Greg A.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.15 MB

english, 2011

22

Rotamer strain as a determinant of protein structural specificity

Greg A. Lazar, Tracy M. Handel, Eric C. Johnson, John R. Desjarlais

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 4.32 MB

english, 1999

23

Solution structure and dynamics of a designed hydrophobic core variant of ubiquitin

Eric C Johnson, Greg A Lazar, John R Desjarlais, Tracy M Handel

Journal:

Year:

1999

Language:

english

File:

PDF, 204 KB

english, 1999

24

Immune suppression in cynomolgus monkeys by XPro9523

Bernett, Matthew J., Chu, Seung Y., Leung, Irene, Moore, Gregory L., Lee, Sung-Hyung, Pong, Erik, Chen, Hsing, Phung, Sheryl, Muchhal, Umesh S., Horton, Holly M., Lazar, Greg A., Desjarlais, John R, S

Journal:

Year:

2013

Language:

english

File:

PDF, 2.20 MB

english, 2013

25

[American Institute of Aeronautics and Astronautics 49th AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition - Orlando, Florida ()] 49th AIAA Aerospace Sciences Meeting including the New Horizons Forum and Aerospace Exposition - Flow and Thermal Properties Induced by Electric Arc Plasma Actuators

Deblauw, Bradley, Lazar, Eli, Kale, Nachiket, Glumac, Nick, Dutton, Craig, Elliott, Greg

Year:

2011

Language:

english

File:

PDF, 1.33 MB

english, 2011

26

A Novel Interface for High-Throughput Analysis of Biotherapeutics by Electrospray Mass Spectrometry

Park, Hae-Min, Winton, Valerie J., Drader, Jared J., Manalili Wheeler, Sheri, Lazar, Greg A., Kelleher, Neil L, Liu, Yichin, Tran, John C., Compton, Philip D.

Journal:

Analytical Chemistry

Year:

2019

File:

PDF, 769 KB

2019

27

Structural stabilization of CNS synapses during postnatal development in rat cortex

Zin Z. Khaing, Lazar Fidler, Nina Nandy, Greg R. Phillips

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 548 KB

english, 2006

28

Designing proteins for therapeutic applications

Greg A Lazar, Shannon A Marshall, Joseph J Plecs, Stephen L Mayo, John R Desjarlais

Journal:

Current Opinion in Structural Biology

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

29

Negative design for improved therapeutic proteins

John R Desjarlais, Greg A Lazar

Journal:

Trends in Biotechnology

Year:

2003

Language:

english

File:

PDF, 73 KB

english, 2003

30

Calculating indirect costs from international PEPFAR implementing partners

Honermann, Brian, Sharp, Alana, Sherwood, Jennifer, Kshetry, Pratima, Jones, Austin, O’Hagan, Richael, Lazar, Laura, Chandra, Christina, Hoffmann, Topher, Millett, Greg, Beck, Eduard J

Journal:

Year:

2018

Language:

english

File:

PDF, 855 KB

english, 2018

31

Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcγRIIb with Fc-engineered antibodies

Seung Y. Chu, Igor Vostiar, Sher Karki, Gregory L. Moore, Greg A. Lazar, Erik Pong, Patrick F. Joyce, David E. Szymkowski, John R. Desjarlais

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 558 KB

english, 2008

32

Optimizing engagement of the immune system by anti-tumor antibodies: an engineer's perspective

John R. Desjarlais, Greg A. Lazar, Eugene A. Zhukovsky, Seung Y. Chu

Journal:

Drug Discovery Today

Year:

2007

Language:

english

File:

PDF, 651 KB

english, 2007

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